Our lab focuses on how remote memories are organized in the cortex, and the molecular and cellular events that underlie their consolidation.
Our lab is interested in how these new neurons contribute to hippocampal memory function. In particular we are interested in how new neurons regulate clearance of memories from the hippocampus (or forgetting).
Gao et al. (2018) Elevation of hippocampal neurogenesis induces a temporally-graded pattern of forgetting of contextual fear memories, J Neuro, published online.
Xia et al. (2017) Parvalbumin-positive interneurons mediate cortical-hippocampal interactions that are necessary for memory consolidation. eLife, in press.
Vetere et al. (2017) Chemogenetic Interrogation of a Brain-wide Fear Memory Network in Mice. Neuron, 94, 363–374.
Xia et al. (2017) Entorhinal Cortical Deep Brain Stimulation Rescues Memory Deficits in Both Young and Old Mice Genetically Engineered to Model Alzheimer’s Disease. Neuropsychoparmacology, in press.
Guskjolen et al. (2017) Age-dependent changes in spatial memory retention and flexibility in mice. Neurobiology of Learning and Memory, 143, 59-66.
Whitehouse Station, NJ
New Delhi, India; Ottawa, ON
Sao Jose dos Campos, Brazil
Chicago, IL, USA
Check out this map of former Jossenlyn/Frankland lab members who have assistant professor level positions around the world