Our lab focuses on how remote memories are organized in the cortex, and the molecular and cellular events that underlie their consolidation.
Our lab is interested in how these new neurons contribute to hippocampal memory function. In particular we are interested in how new neurons regulate clearance of memories from the hippocampus (or forgetting).
Gao, Aijing et al. (2018) Elevation of Hippocampal Neurogenesis Induces a Temporally Graded Pattern of Forgetting of Contextual Fear Memories. J. Neurosci., 38, 13, 3190-3198.
Xia, Frances et al. (2017) Parvalbumin-positive interneurons mediate neocortical-hippocampal interactions that are necessary for memory consolidation. Elife, 6.
Kenney, Justin W et al. (2017) Contextual fear conditioning in zebrafish. Learn. Mem., 24, 10, 516-523.
Richards, Blake A, Frankland, Paul W. (2017) The Persistence and Transience of Memory. Neuron, 94, 6, 1071-1084.
Xia, Frances et al. (2017) Entorhinal Cortical Deep Brain Stimulation Rescues Memory Deficits in Both Young and Old Mice Genetically Engineered to Model Alzheimer's Disease. Neuropsychopharmacology, 42, 13, 2493-2503.
Whitehouse Station, NJ
New Delhi, India; Ottawa, ON
Sao Jose dos Campos, Brazil
Chicago, IL, USA
Check out this map of former Jossenlyn/Frankland lab members who have assistant professor level positions around the world